Autophinib

SKU T4219-1 mg Category Brand:

Price range: 48 CAD through 1,579 CAD

Products Details

Product Description

– Autophinib is a potent autophagy inhibitor with a novel chemotype with IC50 values of 90 and 40 nM for autophagy in starvation induced autophagy assay and rapamycin induced autophagy assay.

Web ID

– T4219

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C14H11ClN6O3

References

– Robke L, et al. Phenotypic Identification of a Novel Autophagy Inhibitor Chemotype Targeting Lipid Kinase VPS34. Angew Chem Int Ed Engl. 2017 Jul 3;56(28):8153-8157.

CAS Number

– 1644443-47-9

Molecular Weight

– C14H11ClN6O3

Compound Purity

– 0.9925

SMILES

– Cc1cc(Nc2cc(Cl)nc(Oc3ccc(cc3)[N+]([O-])=O)n2)n[nH]1

Pathway

– Autophagy|||PI3K/Akt/mTOR signaling

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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