Aurora kinase inhibitor-3

SKU T5524-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 109 CAD through 2,016 CAD

Products Details

Product Description

– Aurora kinase inhibitor-3 (Aurora Kinase Inhibitor III) is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR.

Web ID

– T5524

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H18F3N5O

References

– Zhang Q , Liu Y , Gao F , et al. Discovery of EGFR Selective 4,6-Disubstituted Pyrimidines from a Combinatorial Kinase-Directed Heterocycle Library[J]. Journal of the American Chemical Society, 2006, 128(7):2182-2183.

CAS Number

– 879127-16-9

Molecular Weight

– C21H18F3N5O

Compound Purity

– 0.9891

SMILES

– FC(F)(F)c1cccc(Nc2ccnc(Nc3cccc(NC(=O)C4CC4)c3)n2)c1

Pathway

– Chromatin/Epigenetic|||Cell Cycle/Checkpoint

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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