Download Files:
Atopaxar Hydrobromide
Price range: 411 CAD through 2,848 CAD
Products Details
Product Description
– Atopaxar, a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling. Atopaxar has been investigated for the treatment of Coronary Artery Disease and Acute Coronary Syndrome.
Web ID
– T1986L
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C29H39BrFN3O5
Citations
– 1. Tang W, Huang B, Wang J, et al. A label-free screening approach targeted protease-activated receptor 1 based on dynamic mass redistribution in living cells. RSC Advances. 2017, 7(68): 43005-43013
2. Sun J, Du Y, Zhang X, et al. Discovery and evaluation of Atopaxar hydrobromide, a novel JAK1 and JAK2 inhibitor, selectively induces apoptosis of cancer cells with constitutively activated STAT3. Investigational New Drugs. 2019: 1-9
References
– Changelian PS, et al. Blood. 2008 Feb 15;111(4):2155-7.
CAS Number
– 474550-69-1
Molecular Weight
– C29H39BrFN3O5
Compound Purity
– 1
SMILES
– Br.CCOc1cc2CN(CC(=O)c3cc(N4CCOCC4)c(OC)c(c3)C(C)(C)C)C(=N)c2c(F)c1OCC
Target
– Others
Pathway
– GPCR/G Protein
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock
1000 in stock
