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ATN-224
Price range: 48 CAD through 954 CAD
Products Details
Product Description
– ATN-224 (Bis(choline)tetrathiomolybdate) inhibits SOD1 activity in endothelial cells, an effect that is dose dependent with an IC50 of 17.5±3.7 nM. ATN-224 is an oral Cu2+/Zn2+-superoxide dismutase 1 (SOD1) inhibitor.
Web ID
– T14341
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C10H28MoN2O2S4
Citations
– 1. Lai Y, Yang N, Shi D, et al.Puerarin enhances TFEB-mediated autophagy and attenuates ROS-induced pyroptosis after ischemic injury of random-pattern skin flaps.European Journal of Pharmacology.2024: 176621.
2. Fang P, Cheng S, Lai Y, et al.Pharmacodynamic Insights into Maresin 1: Enhancing Flap Viability via the Keap1/Nrf2 Axis to Control ROS-Driven Apoptosis and Ferroptosis.European Journal of Pharmaceutical Sciences.2024: 106923.
References
– Juarez JC, et al. Copper binding by tetrathiomolybdate attenuates angiogenesis and tumor cell proliferation through the inhibition of superoxide dismutase 1. Clin Cancer Res. 2006 Aug 15;12(16):4974-82.
CAS Number
– 649749-10-0
Molecular Weight
– C10H28MoN2O2S4
Compound Purity
– 0.9945
SMILES
– S=[Mo]([S-])([S-])=S.OCC[N+](C)(C)C.OCC[N+](C)(C)C
Target
– Others
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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