Asimadoline

SKU T4633-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 107 CAD through 475 CAD

Products Details

Product Description

– Asimadoline (EMD-61753) is a proprietary small molecule therapeutic, originally discovered by Merck KGaA of Darmstadt, Germany. Asimadoline was originally developed to treat peripheral pain such as arthritis. Asimadoline is an orally administered agent that acts as a kappa opioid receptor agonist. It has shown encouraging clinical efficacy for the treatment of IBS in a barostat study in IBS patients and has the potential for treating other gastrointestinal diseases.

Web ID

– T4633

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H30N2O2

References

– Camilleri, m. (2008). Novel pharmacology: asimadoline, a κ-opioid agonist, and visceral sensation. Neurogastroenterology & Motility, 20(9), 971-979. doi: 10.1111/j.1365-2982.2008.01183.x

CAS Number

– 153205-46-0

Molecular Weight

– C27H30N2O2

SMILES

– C(C(N([C@H](CN1CC[C@H](O)C1)C2=CC=CC=C2)C)=O)(C3=CC=CC=C3)C4=CC=CC=C4

Pathway

– Endocrinology/Hormones|||Neuroscience|||GPCR/G Protein

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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