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Products Details
Product Description
– AS2521780 is a novel PKCθ selective inhibitor with an IC50 of 0.48 nM.
Web ID
– HY-12663
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C30H41N7OS
References
– [1]Fukahori H, et al. Effect of AS2521780, a novel PKCθ selective inhibitor, on T cell-mediated immunity. Eur J Pharmacol. 2014 Dec 15;745:217-22.
CAS Number
– 1214726-89-2
Molecular Weight
– 547.76
SMILES
– CSC1=C(CNC2=NC=C(C#N)C(NC[C@@]3(C[C@@H](C4)C5NC[C@H]6CC[C@H](O)CC6)C[C@H]4C[C@H]5C3)=N2)C=CC=N1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– PKC
Isoform
– PKCα;PKCδ;PKCε;PKCθ
Pathway
– Epigenetics;TGF-beta/Smad
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
