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Products Details
Product Description
– Artemisiane E (Compound 8) is a potent PI3K/AKT pathway inhibitor with an IC50 of 8.9 μM[1].
Web ID
– HY-N10655
Shipping
– Room temperature
Molecular Formula
– C20H22O5
References
– [1]Dürr L, et al. A Dimerosesquiterpene and Sesquiterpene Lactones from Artemisia argyi Inhibiting Oncogenic PI3K/AKT Signaling in Melanoma Cells. J Nat Prod. 2022 Nov 25;85(11):2557-2569.
CAS Number
– 2618700-77-7
Molecular Weight
– 342.39
SMILES
– C=C1C(O[C@@H]2[C@H]3C(C)=CC(C3=C(C[C@@H]([C@@H]12)OC(/C=C(C)/C)=O)C)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Akt
Pathway
– PI3K/Akt/mTOR
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
