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Apovincaminic acid (hydrochloride salt)
$50 – $175
Products Details
Product Description
– Apovincaminic acid hydrochloride salt is an orally active and brain-penetrant main active metabolite of Vinpocetine (VP). Apovincaminic acid hydrochloride salt exerts a neuroprotective type of action[1][2].
Web ID
– HY-133813A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C20H23ClN2O2
References
– [1]Nyakas C, et, al. Neuroprotective effects of vinpocetine and its major metabolite cis-apovincaminic acid on NMDA-induced neurotoxicity in a rat entorhinal cortex lesion model. CNS Neurosci Ther. Summer 2009;15(2):89-99.|[2]Pudleiner P, et, al. Study on the absorption of vinpocetine and apovincaminic acid. Eur J Drug Metab Pharmacokinet. Oct-Dec 1993;18(4):317-21.|[3]Wang M, et, al. Simultaneous Determination of Vinpocetine and its Major Active Metabolite Apovincaminic Acid in Rats by UPLC-MS/MS and its Application to the Brain Tissue Distribution Study. J Chromatogr Sci. 2018 Mar 1;56(3):225-232.
CAS Number
– 72296-47-0
Molecular Weight
– 358.86
Compound Purity
– 98.0
SMILES
– CC[C@@]12[C@@]3([H])C4=C(CCN3CCC2)C5=CC=CC=C5N4C(C(O)=O)=C1.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– Drug Metabolite
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
