Apomine

SKU T26644-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 118 CAD through 890 CAD

Products Details

Product Description

– Apomine (SR-9223i), an inhibitor of HMG-CoA-reductase, promotes apoptosis of myeloma cells in vitro and has been implicated in the regulation of myeloma in vivo. Apomine accelerates the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase and stimulates low-density lipoprotein receptor activity. Apomine enhances the antitumor effect of lovastatin on myeloma cells by downregulating 3-hydroxy-3-methylglutaryl-CoA reductase.

Web ID

– T26644

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C28H52O7P2

References

– Moriceau G, Roelofs AJ, Brion R, Redini F, Ebetion FH, Rogers MJ, Heymann D. Synergistic inhibitory effect of apomine and lovastatin on osteosarcoma cell growth. Cancer. 2012 Feb 1;118(3):750-60.

CAS Number

– 126411-13-0

Molecular Weight

– C28H52O7P2

Compound Purity

– 1

SMILES

– P(C(P(OC(C)C)(OC(C)C)=O)CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1)(OC(C)C)(OC(C)C)=O

Pathway

– Metabolism

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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