APJ receptor agonist 1
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APJ receptor agonist 1

SKU T39813-5 mg Category Brand:

1,552 CAD

Only 1000 item(s) left in stock.

Products Details

Product Description

– APJ receptor agonist 1, a potent biphenyl acid derivative, acts as an agonist (EC50 of 0.093 nM and 0.12 nM for human and rat APJ receptors, respectively) for the APJ receptor (APJ-R). It exhibits significant in vitro potency towards apelin-13, the endogenous peptidic ligand for the APJ receptor. APJ receptor agonist 1 holds promise for heart failure research.

Web ID

– T39813

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C31H26ClN3O3

References

– Su S, Clarke A, et al. Biphenyl Acid Derivatives as APJ Receptor Agonists. J Med Chem. 2019;62(22):10456-10465.

CAS Number

– 2287153-38-0

Molecular Weight

– C31H26ClN3O3

SMILES

– CCCC(NC(=O)c1ccc(c(c1)C(O)=O)-c1c(Cl)cccc1-c1nc2ccccc2[nH]1)c1ccccc1

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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