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Products Details
Product Description
– Apitolisib (RG 7422), an effective, class I PI3K inhibitor for PI3Kα(IC50=5 nM), PI3Kβ(IC50=27 nM), PI3Kδ(IC50=7 nM), PI3Kγ (IC50=14 nM), is used in trials study of solid cancers, breast cancer, prostate cancer, renal cell carcinoma, and endometrial carcinoma, among others.
Web ID
– T1916
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C23H30N8O3S
References
– Sutherlin DP, et al. J Med Chem, 2011, 54(21), 7579-7587.
CAS Number
– 1032754-93-0
Molecular Weight
– C23H30N8O3S
Compound Purity
– 0.9964
SMILES
– C[C@H](O)C(=O)N1CCN(Cc2sc3c(nc(nc3c2C)-c2cnc(N)nc2)N2CCOCC2)CC1
Target
– Molecular Glues
Pathway
– PI3K/Akt/mTOR signaling|||Apoptosis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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