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Products Details
Product Description
– APC-6860 is a trypsin-like serine protease inhibitor with ( k_i ) values of 0.21, 0.44, 1.5, 16.8, 20, and 30 μM for uPA, trypsin, tryptase, tPA, thrombin, and factor Xa, respectively. It exhibits a selectivity ratio for tPA versus uPA of 80 and has ( k_i ) values of 0.1 and 0.082 μM for human and murine urokinases, respectively. APC-6860 can be utilized for cancer research.
Web ID
– T39029
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C9H7IN2S
References
– Katz BA, et al. Structural basis for selectivity of a small molecule, S1-binding, submicromolar inhibitor of urokinase-type plasminogen activator. Chem Biol. 2000 Apr;7(4):299-312.
CAS Number
– 154628-42-9
Molecular Weight
– C9H7IN2S
SMILES
– NC(=N)c1cc2c(I)cccc2s1
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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