Apaziquone
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Apaziquone

SKU T21316-100 mg Category Brand:

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Products Details

Product Description

– Apaziquone has potential antineoplastic and radiosensitization activities. It is converted to active metabolites in hypoxic cells by intracellular reductases, which are present in greater amounts in hypoxic tumor cells. The active metabolites alkylate DNA, resulting in apoptotic cell death.

Web ID

– T21316

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H16N2O4

References

– Phillips RM, Hendriks HR, Peters GJ; EORTC-Pharmacology and Molecular Mechanism Group. EO9 (Apaziquone): from the clinic to the laboratory and back again. Br J Pharmacol. 2013 Jan;168(1):11-8. doi: 10.1111/j.1476-5381.2012.01996.x. Review. PubMed PMID: 22509926; PubMed Central PMCID: PMC3569998.

CAS Number

– 114560-48-4

Molecular Weight

– C15H16N2O4

SMILES

– C(O)C=1C2=C(N(C)C1/C=C/CO)C(=O)C=C(C2=O)N3CC3

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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