Download Files:
Products Details
Product Description
– Antiviral agent 9 reaches a single-digit picomolar EC50 value (0.006 nM) against HIV-1 and nearly 300-fold higher selectivity index (SI) compared to tenofovir alafenamide fumarate (TAF).
Web ID
– HY-139845
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C38H50N7O8P
References
– [1]Kalčic F, et al. Discovery of Modified Amidate (ProTide) Prodrugs of Tenofovir with Enhanced Antiviral Properties. J Med Chem. 2021 Nov 25;64(22):16425-16449.
Molecular Weight
– 763.82
SMILES
– C[C@@H](C(OC(C)C)=O)NP(OC1=CC=C(C[C@H](NC(OCC2=CC=CC=C2)=O)C(CC3CCCC3)=O)C=C1)(CO[C@H](C)CN4C=NC5=C(N)N=CN=C45)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HIV
Isoform
– HIV-1
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
