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Products Details
Product Description
– Antitumor agent-57 (Compound 3o) is an NQO1-directed antitumor agent. Antitumor agent-57 inhibits tumor cell growth, triggers ROS generation and induces cell apoptosis[1].
Web ID
– HY-146048
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C20H15NO5
References
– [1]Wu LQ, et al. Design, synthesis, and biological evaluation of 4-substituted-3,4-dihydrobenzo[h]quinoline-2,5,6(1H)-triones as NQO1-directed antitumor agents. Eur J Med Chem. 2020 Jul 15;198:112396.
CAS Number
– 2432823-48-6
Molecular Weight
– 349.34
SMILES
– O=C1NC2=C(C(C(C3=CC=CC=C32)=O)=O)C(C4=CC=C(OC)C(O)=C4)C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Reactive Oxygen Species
Pathway
– Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
