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Antimalarial agent 31
Products Details
Product Description
– Antimalarial agent 31 (compound 7k) is an orally active Plasmodium falciparum aspartic protease plasmepsin X (PMX) inhibitor[1].
Web ID
– HY-155130
Shipping
– Room temperature
Molecular Formula
– C36H47N3O4
References
– [1]Vadims Kovada, et al. Macrocyclic Peptidomimetic Plasmepsin X Inhibitors with Potent In Vitro and In Vivo Antimalarial Activity. J Med Chem. 2023 Aug 10;66(15):10658-10680.
Molecular Weight
– 585.78
SMILES
– O[C@@H]([C@@H](NC(C1=CC=CC(C(N(CCC)CCCCC2)=O)=C1)=O)CC3=CC=CC2=C3)CNC(C)(C)C4=CC=CC(OC)=C4
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Parasite
Pathway
– Anti-infection
Product type
– Reference compound
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