Download Files:
Products Details
Product Description
– Antimalarial agent 27 (compound 11a) is an antimalarial agent, potently targeting to P.falciparum (IC50=0.37 μM). Antimalarial agent 27 acts function via P.falciparum DXR (1-deoxy-D-xylulose-5-phosphate reductoisomerase) inhibition (IC50=0.11 μM)[1].
Web ID
– HY-149882
Shipping
– Room temperature
Molecular Formula
– C10H11NNaO5P
References
– [1]Wang X, et al. MEPicides: α,β-unsaturated Fosmidomycin N-Acyl Analogs as Efficient Inhibitors of Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate reductoisomerase. ACS Infect Dis. 2023 Jul 14;9(7):1387-1395.
Molecular Weight
– 279.16
SMILES
– O=C(C1=CC=CC=C1)N(C/C=C/P(O)(O[Na])=O)O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Parasite
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
