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Products Details
Product Description
– Antileishmanial agent-12 (compound 5a) is a potent anti-leishmanial agent. Antileishmanial agent-12 shows antiprotozoal activity against Leishmania brazilensis, Leishmania infantum, and T. cruzi, with IC50 values of 14.9, 21.3 and 9.3 μM, respectively[1].
Web ID
– HY-147857
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C25H21N3O4
References
– [1]Pertino MW, et al. Synthesis, trypanocidal and anti-leishmania activity of new triazole-lapachol and nor-lapachol hybrids. Bioorg Chem. 2020 Oct;103:104122.
CAS Number
– 2482764-71-4
Molecular Weight
– 427.45
SMILES
– O=C(OC(C1=O)=C(/C=C(C)C)C(C2=C1C=CC=C2)=O)CCC3=CN(C4=CC=CC=C4)N=N3
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Parasite
Isoform
– Leishmania
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
