Antifungal agent 30

SKU HY-146464-Get quote Category Tags , ,

Products Details

Product Description

– Antifungal agent 30 (compound A18) is a potent antifungal agent. Antifungal agent 30 shows excellent antifungal activity against Candida albicans (CPCC400616) and Aspergillus fumigatus, with MIC of 0.03 and 0.5 μg/mL, respectively. Antifungal agent 30 also shows excellent antifungal activity against fluconazole-resistant strains. The potent antifungal activity of Antifungal agent 30 mainly causes by hydrogen and coordination bond interaction with the CYP51[1].

Web ID

– HY-146464

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C18H14Cl2F2N2Se

References

– [1]Xu H, et al. Design, synthesis, and biological evaluation of novel miconazole analogues containing selenium as potent antifungal agents. Eur J Med Chem. 2020 Jul 15;198:112360.

CAS Number

– 2422019-91-6

Molecular Weight

– 446.18

SMILES

– FC1=CC(F)=C(C=C1)C([Se]CC2=C(C=C(C=C2)Cl)Cl)CN3C=CN=C3

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– Fungal

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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