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Anticancer agent 30
Products Details
Product Description
– Anticancer agent 30 (compound 6f-Z), a 3-arylidene-2-oxindole derivative, is a selective CDK2 inhibitor with potent anticancer activity[1].
Web ID
– HY-115943
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C22H15ClFNO
References
– [1]Hend A A Abd El-Wahab, et al. New cell cycle checkpoint pathways regulators with 2-Oxo-indoline scaffold as potential anticancer agents: Design, synthesis, biological activities and in silico studies. Bioorg Chem. 2022 Jan 15;120:105622.
CAS Number
– 2907774-88-1
Molecular Weight
– 363.81
SMILES
– O=C1N(CC2=CC=C(F)C=C2)C3=C(C=CC=C3)/C1=C/C4=CC=C(Cl)C=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– CDK
Isoform
– CDK2
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
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