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Products Details
Product Description
– Anticancer agent 29 (Compd E/Z-6f) is an anticancer agent, with IC50 values of 0.054 μM, 0.127 μM, 0.129 μM, 0.396 μM for CDK2, CDK1, CDK4 and CDK6, respectively[1].
Web ID
– HY-115942
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C22H15ClFNO
References
– [1]Hend A A Abd El-Wahab, et al. New cell cycle checkpoint pathways regulators with 2-Oxo-indoline scaffold as potential anticancer agents: Design, synthesis, biological activities and in silico studies. Bioorg Chem. 2022 Jan 15;120:105622.
CAS Number
– 2907774-89-2
Molecular Weight
– 363.81
SMILES
– O=C1/C(C2=CC=CC=C2N1CC3=CC=C(C=C3)F)=C/C4=CC=C(C=C4)Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– CDK
Isoform
– CDK1;CDK2;CDK4;CDK6
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
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