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Products Details
Product Description
– Anticancer agent 105 is a compound based on thienopyrimidine scaffold, with with good safety and anticancer properties. Anticancer agent 105 shows selective toxicity towards melanoma cancer, and induces apoptosis. And Anticancer agent 105 significantly inhibits the metastatic nodules, even in pulmonary metastatic melanoma mouse model[1].
Web ID
– HY-149949
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H24KN3O6S
References
– [1]Rogova A, et al. Synthesis of thieno[3,2-e]pyrrolo[1,2-a]pyrimidine derivatives and their precursors containing 2-aminothiophenes fragments as anticancer agents for therapy of pulmonary metastatic melanoma. Eur J Med Chem. 2023 Jun 5;254:115325.
CAS Number
– 2450987-57-0
Molecular Weight
– 533.64
SMILES
– O=C(OCC)C1=C(NC(/C(O[K])=C(C(N)=O)C#N)=CC(C2=CC=C(OC)C=C2)=O)SC3=C1CCCC3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Reference compound
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