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Products Details
Product Description
– Antibacterial agent 91 (Compound 36b) is a triple-site aminoacyl-tRNA synthetase (aaRS) inhibitor with an IC50 of 2.10 μM against Salmonella enterica threonyl-tRNA synthetase (SeThrRS). Antibacterial agent 91 exhibits antibacterial activities[1].
Web ID
– HY-146264
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C33H31BrClN5O4
References
– [1]Cai Z, et al. Design, Synthesis, and Proof-of-Concept of Triple-Site Inhibitors against Aminoacyl-tRNA Synthetases. J Med Chem. 2022 Apr 14;65(7):5800-5820.
Molecular Weight
– 676.99
SMILES
– O=C(NC[C@@H](C1=CC(C2=CC3=C(C=C2)C=CC=C3)=CC=C1)NC([C@@H](N)[C@@H](C)O)=O)CCN4C=NC5=C(C4=O)C=C(Cl)C(Br)=C5
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Aminoacyl-tRNA Synthetase;Bacterial
Pathway
– Anti-infection;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
