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Products Details
Product Description
– anti-TNBC agent-2 (3j) an anti-Triple negative breast cancer (TNBC) purine derivative. anti-TNBC agent-2 induces MDA-MB-231 cells apoptosis, and inhibits its migration and angiogenesis. anti-TNBC agent-2 inhibits tumor growth and metastasis and reduces the expression of Ki67 and CD31 protein in TNBC xenograft models. anti-TNBC agent-2 can be used for Triple negative breast cancer (TNBC) research[1].
Web ID
– HY-156077
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C28H37ClFN7O
References
– [1]Zhang Q, et al. Synthesis and mechanism of action of new purine derivatives against triple negative breast cancer. Eur J Med Chem. 2023 Sep 7;261:115797.
CAS Number
– 2422001-22-5
Molecular Weight
– 542.09
SMILES
– FC1=CC=C(C=C1Cl)CNC2=C3N=CN(C3=NC(N4CCC(CC4)C5CCN(CC5)CCO)=N2)CC6CC6
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Reference compound
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