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Products Details
Product Description
– Anti-MRSA agent 7 (Compound 12) is a potent antibacterial agent. Anti-MRSA agent 7 inhibits S. aureus DNA gyrase, E. coli DNA gyrase, S. aureus topo IV and E. coli topo IV with IC50s of 0.185, 0.365, 0.341 and 0.059 μM, respectively[1].
Web ID
– HY-149271
Shipping
– Room temperature
Molecular Formula
– C22H20BrF2N3O4
References
– [1]Kokot M, et al. Amide containing NBTI antibacterials with reduced hERG inhibition, retained antimicrobial activity against gram-positive bacteria and in vivo efficacy. Eur J Med Chem. 2023 Mar 15;250:115160.
Molecular Weight
– 508.31
SMILES
– COC1=NC2=C(N=CC=C2OC[C@H]3CC[C@@H](CO3)NC(C4=CC(F)=C(C(F)=C4)Br)=O)C=C1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial;DNA/RNA Synthesis;Topoisomerase
Isoform
– Topoisomerase
Pathway
– Anti-infection;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
