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Anti-inflammatory agent 46
SKU
HY-155551-Get quote
Category Reference compound
Tags Immunology/Inflammation, Inflammation/Immunology, NO Synthase
Products Details
Product Description
– Anti-inflammatory agent 46 (compound 7h) is an anti-inflammatory agent with nitric oxide (NO) inhibitory effect. Anti-inflammatory agent 46 binds to iNOS with low energies, inhibits swelling in mice (at dose of 10 mg/kg)[1].
Web ID
– HY-155551
Shipping
– Room temperature
Molecular Formula
– C24H19FN2O3S
References
– [1]Akhtar M, et al. Anti-inflammatory efficacy and relevant SAR investigations of novel chiral pyrazolo isoquinoline derivatives: Design, synthesis, in-vitro, in-vivo, and computational studies targeting iNOS. Eur J Med Chem. 2023 Aug 5;256:115412.
CAS Number
– 2925586-96-3
Molecular Weight
– 434.48
SMILES
– O=S(N1N2[C@@](C3=CC=CC=C3C=C2)([H])[C@@H](C4=CC=C(C=C4)F)C1=O)(C5=CC=C(C=C5)C)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– NO Synthase
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.