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Products Details
Product Description
– ANO1-IN-2 (Compound 10q) is a selective ANO1 channel blocker with an IC50 of 1.75 μM and 7.43 μM against ANO1 and ANO2, respectively. ANO1-IN-2 suppresses strongly proliferation of glioblastoma cells[1].
Web ID
– HY-146321
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C16H14ClN3O2S2
References
– [1]Choi SH, et al. Anti-glioma effects of 2-aminothiophene-3-carboxamide derivatives, ANO1 channel blockers. Eur J Med Chem. 2020 Dec 15;208:112688.
CAS Number
– 637314-12-6
Molecular Weight
– 379.88
SMILES
– NC(C1=C(SC2=C1CCC2)NC(NC(C3=CC=C(C=C3)Cl)=O)=S)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Chloride Channel
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
