Andrastin A

$574

Only 1000 item(s) left in stock.

Products Details

Product Description

– Andrastin A meroterpenoid compound, is a farnesyltransferase inhibitor. Andrastin A inhibits the efflux of anticancer compounds from multidrug-resistant cancer cells. Andrastin A can be isolated from Penicillium species[1][2].

Web ID

– HY-129279

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C28H38O7

References

– [1]Nielsen KF, et al. Andrastins A-D, Penicillium roqueforti Metabolites consistently produced in blue-mold-ripened cheese. J Agric Food Chem. 2005 Apr 20;53(8):2908-13. |[2]Rojas-Aedo JF, et al. The Biosynthetic Gene Cluster for Andrastin A in Penicillium roqueforti. Front Microbiol. 2017 May 5;8:813.

CAS Number

– 174232-42-9

Molecular Weight

– 486.60

SMILES

– CC1=C[C@@]2([C@](C)(CC[C@@]3(C(C)([C@H](CC[C@]32C=O)OC(C)=O)C)[H])[C@@](C(OC)=O)([C@@]1(C4=O)C)C(C4C)=O)[H]

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Farnesyl Transferase

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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