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AN-3485
SKU
HY-18325-10 mg
Category Reference compound
Tags Immunology/Inflammation, Inflammation/Immunology, Toll-like Receptor (TLR)
$260 – $2,100
Products Details
Product Description
– AN-3485 is a benzoxaborole analog, Toll-Like Receptor(TLR) inhibitor with IC50 values ranging from 18 to 580 nM.
Web ID
– HY-18325
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C14H13BClNO3
References
– [1]Dong C, et al. Inhibition of Toll-like receptor-mediated inflammation in vitro and in vivo by a novelbenzoxaborole. J Pharmacol Exp Ther. 2013 Feb;344(2):436-46.
CAS Number
– 1213827-99-6
Molecular Weight
– 289.52
Compound Purity
– 95.63
SMILES
– NCC1=CC(Cl)=C(OC2=CC=C(COB3O)C3=C2)C=C1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 5 mg/mL (ultrasonic)
Target
– Toll-like Receptor (TLR)
Isoform
– TLR2;TLR3;TLR4
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.