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Products Details
Product Description
– AMX12006 is a potent, selective and orally active EP4 antagonist with an IC50 value of 4.3 nM. AMX12006 shows cytotoxic and antitumor activity[1].
Web ID
– HY-149290
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C26H22F3N3O3
References
– [1]Debasis Das, et al. Discovery of Novel, Selective Prostaglandin EP4 Receptor Antagonists with Efficacy in Cancer Models. ACS Med. Chem. Lett. 2023.
CAS Number
– 2639775-01-0
Molecular Weight
– 481.47
SMILES
– O=C(N[C@@H](C)C1=CC=C(C(O)=O)C=C1)C2=C(C3=CC=CC=C3N2C)NC4=CC(C(F)(F)F)=CC=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Prostaglandin Receptor
Isoform
– EP
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
