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AMPK activator 2 (hydrochloride)
$240 – $385
Products Details
Product Description
– AMPK activator 2 (compound 7a) hydrochloride, a fluorine-containing proguanil derivative, up-regulates AMPK signal pathway and downregulates mTOR/4EBP1/p70S6K. AMPK activator 2 hydrochloride inhibits proliferation and migration of human cancer cell lines (UMUC3, T24, A549)[1].
Web ID
– HY-130723A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Molecular Formula
– C13H19ClF3N5
References
– [1]Di Xiao, et al. Synthesis, biological evaluation and anti-proliferative mechanism of fluorine-containing proguanil derivatives. Bioorg Med Chem. 2020 Jan 15;28(2):115258.
Molecular Weight
– 337.77
Compound Purity
– 99.65
SMILES
– N=C(NC(NC1=CC=C(C(F)(F)F)C=C1)=N)NCC(C)C.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– AMPK
Isoform
– AMPK
Pathway
– Epigenetics;PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
