Amphotericin B

SKU T1067-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 50 CAD through 157 CAD

Products Details

Product Description

– Amphotericin B (NSC-527017) is a polyene antifungal agent with broad-spectrum activity against many fungal species. Amphotericin B irreversibly binds to ergosterol and disrupts the integrity of cell membranes, resulting in antifungal activity.

Web ID

– T1067

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C47H73NO17

Citations

– 1. Sun C, Su J, Wang J, et al.Lycium barbarum polysaccharide increases thermogenesis and energy metabolism through modulation of the gut microbiota to confer resistance to cold temperatures.The FASEB Journal.2024, 38(17): e70010. 2. Wu X, Wang Z, Liang Z, et al.Pleiotropic role of CCR9/CCL25 signaling in adriamycin-induced cardiomyopathy.Journal of Advanced Research.2024 3. Diversity and Antifungal Susceptibilities of Yeasts from Mangroves in Hong Kong, China-A One Health Aspect

References

– Grela E, et al. Imaging of human cells exposed to an antifungal antibiotic amphotericin B reveals the mechanisms associated with the drug toxicity and cell defence. Sci Rep. 2018 Sep 14;8(1):14067.

CAS Number

– 1397-89-3

Molecular Weight

– C47H73NO17

Compound Purity

– ≥98%

SMILES

– [H][C@]12C[C@@]([H])(O[C@@H]3O[C@H](C)[C@@H](O)[C@H](N)[C@@H]3O)C=CC=CC=CC=CC=CC=CC=C[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@@H](O)C[C@@H](O)CC[C@H](O)[C@@H](O)C[C@@H](O)C[C@](O)(C[C@H](O)[C@H]1C(O)=O)O2

Target

– Others

Pathway

– Microbiology/Virology

Product type

– Natural Product

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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