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Products Details
Product Description
– AMPD2 inhibitor 2 (compound 21) is a potent AMP deaminase 2 (AMPD2) inhibitor with IC50s of 0.1 μM and 0.28μM for hAMPD2 and mAMPD2, respectively. AMPD2 inhibitor 2 has the potential for evaluating the physiological role of AMPD2 in mice maintained on a high fat diet[1].
Web ID
– HY-152199
Shipping
– Room temperature
Molecular Formula
– C26H27F2N3O3
References
– [1]Yuki Kitao, et al. The discovery of 3,3-dimethyl-1,2,3,4-tetrahydroquinoxaline-1-carboxamides as AMPD2 inhibitors with a novel mechanism of action. Bioorg Med Chem Lett. 2022 Dec 20;80:129110.
Molecular Weight
– 467.51
SMILES
– CC1(CN(C2=CC=C(C(F)=C2N1CC3=CC=C(C=C3)COC4=CC=C(C=C4)CO)F)C(N)=O)C
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Adenosine Deaminase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
