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Amino-Tri-(carboxyethoxymethyl)-methane (hydrochloride)
SKU
HY-117519A-100 mg
Category ADC Related
Tags ADC Linker;PROTAC Linkers, Antibody-drug Conjugate/ADC Related;PROTAC, Cancer
$125 – $320
Products Details
Product Description
– Amino-Tri-(carboxyethoxymethyl)-methane hydrochloride is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-Tri-(carboxyethoxymethyl)-methan hydrochloride is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1][2].
Web ID
– HY-117519A
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C13H24ClNO9
References
– [1]Markus Ribbert, et al. Self coupling recombinant antibody fusion proteins. WO2009013359A2.|[2]David Margulies, et al. Fluorescent molecular sensor for targeting changes in protein surfaces, and methods of use thereof. WO2015166491A2.
CAS Number
– 1416771-72-6
Molecular Weight
– 373.78
SMILES
– O=C(CCOCC(COCCC(O)=O)(COCCC(O)=O)N)O.Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Linker;PROTAC Linkers
Pathway
– Antibody-drug Conjugate/ADC Related;PROTAC
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.