Amino-Tri-(carboxyethoxymethyl)-methane (hydrochloride)

$125$320

Products Details

Product Description

– Amino-Tri-(carboxyethoxymethyl)-methane hydrochloride is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Amino-Tri-(carboxyethoxymethyl)-methan hydrochloride is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1][2].

Web ID

– HY-117519A

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C13H24ClNO9

References

– [1]Markus Ribbert, et al. Self coupling recombinant antibody fusion proteins. WO2009013359A2.|[2]David Margulies, et al. Fluorescent molecular sensor for targeting changes in protein surfaces, and methods of use thereof. WO2015166491A2.

CAS Number

– 1416771-72-6

Molecular Weight

– 373.78

SMILES

– O=C(CCOCC(COCCC(O)=O)(COCCC(O)=O)N)O.Cl

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– ADC Linker;PROTAC Linkers

Pathway

– Antibody-drug Conjugate/ADC Related;PROTAC

Product type

– ADC Related

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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