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Amino-Tri-(carboxyethoxymethyl)-methane
$125 – $320
Products Details
Product Description
– Amino-Tri-(carboxyethoxymethyl)-methane is a cleavable PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Amino-Tri-(carboxyethoxymethyl)-methan is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[2].
Web ID
– HY-117519
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C13H23NO9
References
– [1]Markus Ribbert, et al. Self coupling recombinant antibody fusion proteins. WO2009013359A2.|[2]David Margulies, et al. Fluorescent molecular sensor for targeting changes in protein surfaces, and methods of use thereof. WO2015166491A2.
CAS Number
– 174362-95-9
Molecular Weight
– 337.32
Compound Purity
– 98.0
SMILES
– NC(COCCC(O)=O)(COCCC(O)=O)COCCC(O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Linker;PROTAC Linkers
Isoform
– Cleavable Linker;PEG Linkers
Pathway
– Antibody-drug Conjugate/ADC Related;PROTAC
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
