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Amgen-23
$250 – $2,100
Products Details
Product Description
– Amgen-23 (compound 23) is a potent sphingosine kinases (SPHK) inhibitor with IC50 values of 20 nM and 1.6 μM for SPHK1 and SPHK2, respectively. Amgen-23 can be used for researching anticancer[1].
Web ID
– HY-147282
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C23H25Cl2N3O2S
References
– [1]Gustin DJ, et al. Structure guided design of a series of sphingosine kinase (SphK) inhibitors. Bioorg Med Chem Lett. 2013 Aug 15;23(16):4608-16.
CAS Number
– 1448706-15-7
Molecular Weight
– 478.43
Compound Purity
– 99.00
SMILES
– ClC(C=C1C2=CSC(NC3=CC=C(C=C3)CCN4[C@H](C[C@H](CC4)O)CO)=N2)=C(C=C1)Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– SphK
Isoform
– SphK1;SphK2
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
