AMG-337

SKU T3209-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 54 CAD through 1,261 CAD

Products Details

Product Description

– AMG-337 is an effective and highly specific ATP-competitive MET kinase inhibitor. In enzymatic assays, AMG-337(AMG337) inhibits MET kinase activity (IC50: < 5 nM).

Web ID

– T3209

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H22FN7O3

Citations

– 1. Huang Y, Guo Y, Zhou Y, et al.Tivantinib alleviates inflammatory diseases by directly targeting NLRP3.iScience.2023

References

– Hughes PE, et al. Mol Cancer Ther. 2016, 15(7):1568-1579.

CAS Number

– 1173699-31-4

Molecular Weight

– C23H22FN7O3

Compound Purity

– 0.9982

SMILES

– COCCOc1cnc2ccn([C@H](C)c3nnc4c(F)cc(cn34)-c3cnn(C)c3)c(=O)c2c1

Target

– Nrf2

Pathway

– Tyrosine Kinase/Adaptors

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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