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Alovudine
$28 – $176
Products Details
Product Description
– Alovudine (3′-Fluoro-3′-deoxythymidine) is a marker of DNA synthesis that is less susceptible to inflammatory changes than 18F-Fluorodeoxyglucose (FDG) and thus is a better biomarker in pancreatic cancer. Alovudine shows anti-orthopoxvirus activity[1][2].
Web ID
– HY-B1516
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C10H13FN2O4
References
– [1]Smee DF, et al. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 2003 Jan;57(1-2):41-52.|[2]Challapalli A, et al. 3′-Deoxy-3′-<sup>18</sup>F-fluorothymidine positron emission tomography as an early predictor of disease progression in patients with advanced and metastatic pancreatic cancer. Eur J Nucl Med Mol Imaging. 2015 May;42(6):831-40.
CAS Number
– 25526-93-6
Molecular Weight
– 244.22
Compound Purity
– 99.78
SMILES
– OC[C@@H]1[C@@H](F)C[C@H](N2C(NC(C(C)=C2)=O)=O)O1
Clinical Information
– Phase 2
Research Area
– Cancer; Infection
Solubility
– DMSO : 100 mg/mL (ultrasonic)|H2O : ≥ 25 mg/mL
Target
– DNA/RNA Synthesis;Orthopoxvirus
Pathway
– Anti-infection;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
