Download Files:
Products Details
Product Description
– Alkannin is a potent and specific inhibitor of tumor-specific pyruvate kinase-M2 (PKM2). Alkannin does not inhibit PKM1 and pyruvate kinase-L (PKL). Alkannin acts as a potential anticancer agent[1].
Web ID
– HY-119874
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C16H16O5
References
– [1]J Chen, et al. Shikonin and its analogs inhibit cancer cell glycolysis by targeting tumor pyruvate kinase-M2. Oncogene. 2011 Oct 20;30(42):4297-306.
CAS Number
– 23444-65-7
Molecular Weight
– 288.30
SMILES
– OC1=C(C=C(C2=C1C(C=CC2=O)=O)O)[C@H](C/C=C(C)C)O
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Pyruvate Kinase
Pathway
– Metabolic Enzyme/Protease
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
