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Alflutinib
Price range: 360 CAD through 3,008 CAD
Products Details
Product Description
– Alflutinib (Firmonertinib) is an inhibitor of EGFR, and its targets including EGFR activating mutations and T790M, thus leading to tumor growth inhibition.
Web ID
– T22254
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C28H31F3N8O2
Citations
– 1. Wei X, Zhang G, Liu Q, et al.Almonertinib and alflutinib show novel inhibition on rare EGFR S768I mutant cells.Clinical and Translational Oncology.2024: 1-16.
References
– Liu XY, et al. Alflutinib (AST2818), primarily metabolized by CYP3A4, is a potent CYP3A4 inducer. Acta Pharmacol Sin. 2020 Oct;41(10):1366-1376.
CAS Number
– 1869057-83-9
Molecular Weight
– C28H31F3N8O2
Compound Purity
– 0.9961
SMILES
– CN1C=C(C=2C1=CC=CC2)C3=NC(NC4=C(OCC(F)(F)F)N=C(N(CCN(C)C)C)C(NC(C=C)=O)=C4)=NC=C3
Target
– ADC Linker
Pathway
– Angiogenesis|||Metabolism|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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