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ALDH3A1-IN-1

$70$600

Products Details

Product Description

– ALDH3A1-IN-1 (Compound 18) is a potent inhibitor of ALDH3A1 with an IC50 of 1.61 μM. ALDH3A1-IN-1 is more potent than DEAB against patient-derived primary prostate tumor epithelial cells, as single agents or in combination research with docetaxel[1].

Web ID

– HY-144670

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C13H18N2O3

References

– [1]Ibrahim AIM, et al. Expansion of the 4-(Diethylamino)benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer. J Med Chem. 2022 Mar 10;65(5):3833-3848.

CAS Number

– 1039855-56-5

Molecular Weight

– 250.29

Compound Purity

– 95.0

SMILES

– O=CC1=CC([N+]([O-])=O)=C(C=C1)N(CCC)CCC

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)

Target

– Aldehyde Dehydrogenase (ALDH)

Isoform

– ALDH3

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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