ALCAM Protein, Human, Recombinant (His & Avi), Biotinylated

SKU TMPK-00340-100 μg Category Brand:

Price range: 1,302 CAD through 5,200 CAD

Products Details

Product Description

– Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression promote BM formation in NSCLC through increased tumor cell dissemination and interaction with the brain endothelial cells. Therefore, ALCAM could be targeted to reduce the occurrence of BM. ALCAM Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 58.9 kDa and the accession number is Q13740-1.

Web ID

– TMPK-00340

Storage Temperature

– -20℃

Shipping

– Blue Ice

References

– Münsterberg J, et al. ALCAM contributes to brain metastasis formation in non-small-cell lung cancer through interaction with the vascular endothelium. Neuro Oncol. 2020 Jul 7;22(7):955-966. doi: 10.1093/neuonc/noaa028. PMID: 32064501; PMCID: PMC7339886.

Molecular Weight

Product type

– Recombinant-Protein

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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