Download Files:
ALC-0315
$190 – $620
Products Details
Product Description
– ALC-0315 is an ionisable aminolipid that is responsible for mRNA compaction and aids mRNA cellular delivery and its cytoplasmic release through suspected endosomal destabilization. ALC-0315 can be used to form lipid nanoparticle (LNP) delivery vehicles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine[1].
Web ID
– HY-138170
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Molecular Formula
– C48H95NO5
References
– [1]Moghimi SM. Allergic Reactions and Anaphylaxis to LNP-Based COVID-19 Vaccines. Mol Ther. 2021;29(3):898-900.|[2]Ferraresso F, Strilchuk AW, Juang LJ, Poole LG, Luyendyk JP, Kastrup CJ. Comparison of DLin-MC3-DMA and ALC-0315 for siRNA Delivery to Hepatocytes and Hepatic Stellate Cells. Mol Pharm. 2022;19(7):2175-2182.
CAS Number
– 2036272-55-4
Molecular Weight
– 766.27
Compound Purity
– 99.81
SMILES
– OCCCCN(CCCCCCOC(C(CCCCCC)CCCCCCCC)=O)CCCCCCOC(C(CCCCCC)CCCCCCCC)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– DMSO : 50 mg/mL (ultrasonic)|Ethanol : 100 mg/mL (ultrasonic)
Target
– Liposome;SARS-CoV
Pathway
– Anti-infection;Metabolic Enzyme/Protease
Product type
– Oligonucleotides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
