Products Details

Product Description

– Alatrofloxacin, the parenteral proagent of Trovafloxacin, is a fluoronaphthyridone which contains an L-alanyl-L-alanyl salt. Alatrofloxacin functions similar to other fluoroquinolone antibiotics in that it not only has antibiotic activity to kill invading organisms by interfering with DNA synthesis, it possesses immunosuppressive activity[1].

Web ID

– HY-16035

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C26H25F3N6O5

References

– [1]Hall IH, et al. Effects of alatrofloxacin, the parental prodrug of trovafloxacin, on phagocytic, anti-inflammatory and immunomodulation events of human THP-1 monocytes. Biomed Pharmacother. 2003;57(8):359-365.

CAS Number

– 146961-76-4

Molecular Weight

– 558.5091096

SMILES

– O=C1C2=CC(F)=C(N3C[C@@]4([H])[C@@]([C@@H]4NC([C@H](C)NC([C@@H](N)C)=O)=O)([H])C3)N=C2N(C5=C(C=C(C=C5)F)F)C=C1C(O)=O

Clinical Information

– Launched

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Antibiotic;DNA/RNA Synthesis

Isoform

– Quinolone

Pathway

– Anti-infection;Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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