AL 6598

SKU T38113-1 mg Category Brand:

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Products Details

Product Description

– Elevated intraocular pressure (IOP) is an important risk factor in developing glaucoma. Certain prostaglandins such as PGF2α and PGD2, have been shown to reduce IOP. AL 6598 is the isopropyl ester prodrug of AL 6556, a PGD2 receptor agonist that binds to DP receptors with a Ki value of 3.2 μM and demonstrates an EC50 value of 0.80 μM in an in vitro functional assay. Designed to enhance corneal absorption, AL 6598 produces a maximum 53% drop in IOP of the ocular hypertensive monkey with a 1 μg dose given twice daily.

Web ID

– T38113

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H39ClO5

CAS Number

– 170291-06-2

Molecular Weight

– C23H39ClO5

SMILES

– C(C[C@@H](O)C1CCCCC1)[C@@H]2[C@@H](C/C=CCOCC(OC(C)C)=O)[C@H](Cl)C[C@H]2O

Pathway

– Others

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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