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AL-34662
SKU
HY-125641-5mg
Category Reference compound
Tags 5-HT Receptor;Adrenergic Receptor, Cardiovascular Disease, GPCR/G Protein;Neuronal Signaling
$122
Only 1000 item(s) left in stock.
Products Details
Product Description
– AL-34662 is a selective 5-HT2A receptoragonist (IC50: 0.77 nM and 1.5 nM for rat and human 5-HT2 receptor). AL-34662 is also a weak α-1D adrenergic agonist activity (EC50:0.4 μM). AL-34662 is an ocular hypotensive agent[1][2].
Web ID
– HY-125641
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C10H13N3O
References
– [1]Sharif NA, et al. AL-34662: a potent, selective, and efficacious ocular hypotensive serotonin-2 receptor agonist. J Ocul Pharmacol Ther. 2007 Feb;23(1):1-13.|[2]Asano T, et al. Ameliorative effect of chlorpromazine hydrochloride on visceral hypersensitivity in rats: possible involvement of 5-HT2A receptor. Br J Pharmacol. 2017 Oct;174(19):3370-3381.
CAS Number
– 210580-75-9
Molecular Weight
– 191.23
Compound Purity
– 99.19
SMILES
– OC1=CC2=C(C=C1)C=NN2C[C@@H](N)C
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– DMSO : 62.5 mg/mL (ultrasonic)
Target
– 5-HT Receptor;Adrenergic Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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