AKT inhibitor VIII

SKU T3346-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 70 CAD through 1,075 CAD

Products Details

Product Description

– AKT inhibitor VIII (AKTi-1/2) is a highly specific inhibitor of Akt1/2, with IC50 values of 58 nM and 210 nM respectively, demonstrating approximately 36-fold greater selectivity for Akt1 over Akt3.

Web ID

– T3346

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C34H29N7O

Citations

– 1. Huang Q, Ru Y, Luo Y, et al.Identification of a targeted ACSL4 inhibitor to treat ferroptosis-related diseases.Science Advances.2024, 10(13): eadk1200.

References

– Lindsley CW, et al. Bioorg Med Chem Lett. 2005, 15(3), 761-764.

CAS Number

– 612847-09-3

Molecular Weight

– C34H29N7O

Compound Purity

– 0.9877

SMILES

– O=c1[nH]c2ccccc2n1C1CCN(Cc2ccc(cc2)-c2nc3cc4[nH]cnc4cc3nc2-c2ccccc2)CC1

Pathway

– Cytoskeletal Signaling|||Apoptosis|||PI3K/Akt/mTOR signaling

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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