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Products Details
Product Description
– AKT-IN-8 is a potent AKT inhibitor with IC50s of 4.46, 2.44, and 9.47 nM for AKT1, AKT2, and AKT3, respectively[1].
Web ID
– HY-143611
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C22H25ClN6O3
References
– [1]Fused tetracyclic derivative, preparation method therefor, and medical use thereof. WO2021121276A1.
CAS Number
– 2654026-13-6
Molecular Weight
– 456.93
SMILES
– OCC[C@@H](C1=CC=C(C=C1)Cl)NC([C@@]2(C[C@]3([H])N(CC2)C4=C5C(OC3)=CN=C5N=CN4)N)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Akt
Isoform
– Akt1;Akt2;Akt3
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
