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Products Details
Product Description
– AKT-IN-13 (compound 4b) is a potent Akt inhibitor with IC50s of 1.6 nM, 2.4 nM and 0.3 nM for Akt1, Akt2 and Akt3, respectively. AKT-IN-13 can be used for researching anticancer[1].
Web ID
– HY-147937
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C24H31ClN6O2
References
– [1]Ma C, et al. Discovery of Clinical Candidate NTQ1062 as a Potent and Bioavailable Akt Inhibitor for the Treatment of Human Tumors. J Med Chem. 2022 Jun 23;65(12):8144-8168.
CAS Number
– 2459489-51-9
Molecular Weight
– 470.99
SMILES
– O=C(N1CCN(CC1)C2=C3C(NC(C[C@H]3C)=O)=NC=N2)[C@@H](C4=CC=C(C=C4)Cl)CNC(C)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Akt
Isoform
– Akt1;Akt2;Akt3
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
