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Afuresertib
Price range: 53 CAD through 1,744 CAD
Products Details
Product Description
– Afuresertib (GSK2110183) is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity.
Web ID
– T1911
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C18H17Cl2FN4OS
Citations
– 1. Wang J, Xu X, Wang T, et al. Ceritinib increases sensitivity of AKT inhibitors to gastric cancer. European Journal of Pharmacology. 2021: 173879.
2. Wang J, Xu X, Wang T, et al. Ceritinib increases sensitivity of AKT inhibitors to gastric cancer. European Journal of Pharmacology. 2021: 173879.
3. Huang Q, Ru Y, Luo Y, et al.Identification of a targeted ACSL4 inhibitor to treat ferroptosis-related diseases.Science Advances.2024, 10(13): eadk1200.
4. Xu X, Ma S, Liu Z, et al.EV71 5’UTR interacts with 3D protein affecting replication through the AKT-mTOR pathway.Virology Journal.2024, 21.
References
– Dumble M, et al. PLoS One, 2014, 9(6):e100880.
CAS Number
– 1047644-62-1
Molecular Weight
– C18H17Cl2FN4OS
Compound Purity
– 0.9917
SMILES
– Cn1ncc(Cl)c1-c1cc(sc1Cl)C(=O)N[C@H](CN)Cc1cccc(F)c1
Target
– Others
Pathway
– Stem Cells|||Cytoskeletal Signaling|||Chromatin/Epigenetic|||PI3K/Akt/mTOR signaling|||Cell Cycle/Checkpoint
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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